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M Bishr Omary Selected Research

Porphyrias (Porphyria)

1/2021Protein-aggregating ability of different protoporphyrin-IX nanostructures is dependent on their oxidation and protein-binding capacity.
1/2019Loss of hepatocyte β-catenin protects mice from experimental porphyria-associated liver injury.
1/2019Oxygen and Conformation Dependent Protein Oxidation and Aggregation by Porphyrins in Hepatocytes and Light-Exposed Cells.
1/2019Porphyrin-Induced Protein Oxidation and Aggregation as a Mechanism of Porphyria-Associated Cell Injury.
6/2017Intermediate filament proteins of digestive organs: physiology and pathophysiology.
1/2016A precursor-inducible zebrafish model of acute protoporphyria with hepatic protein aggregation and multiorganelle stress.
9/2015Ambient Light Promotes Selective Subcellular Proteotoxicity after Endogenous and Exogenous Porphyrinogenic Stress.
7/2013Lamin aggregation is an early sensor of porphyria-induced liver injury.
4/2010Gender dimorphic formation of mouse Mallory-Denk bodies and the role of xenobiotic metabolism and oxidative stress.

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M Bishr Omary Research Topics

Disease

33Liver Diseases (Liver Disease)
01/2018 - 02/2002
15Fibrosis (Cirrhosis)
11/2023 - 05/2003
9Porphyrias (Porphyria)
01/2021 - 04/2010
8End Stage Liver Disease
11/2023 - 09/2005
8Neoplasms (Cancer)
10/2019 - 09/2003
8Pancreatitis
01/2018 - 10/2004
7Acute Liver Failure (Fulminant Hepatic Failure)
11/2023 - 09/2010
6Non-alcoholic Fatty Liver Disease
01/2023 - 11/2013
6Chronic Hepatitis C
01/2012 - 06/2006
5Fatty Liver
01/2018 - 11/2003
5Colitis
06/2015 - 03/2004
5Inflammation (Inflammations)
12/2014 - 03/2004
5Infections
01/2012 - 08/2004
4Epidermolysis Bullosa Simplex (Epidermolysis Bullosa Herpetiformis Dowling Meara)
12/2023 - 12/2022
4Hepatocellular Carcinoma (Hepatoma)
01/2019 - 08/2003
4Liver Cirrhosis (Hepatic Cirrhosis)
11/2017 - 05/2003
3Skin Diseases (Skin Disease)
12/2023 - 07/2003
3Chemical and Drug Induced Liver Injury
01/2023 - 05/2003
3Laminopathies
01/2020 - 07/2013
3Liver Failure
01/2019 - 01/2013
3Hypoxia (Hypoxemia)
01/2018 - 10/2012
3Necrosis
01/2016 - 01/2013
3Disease Progression
08/2009 - 05/2005
2Insulin Resistance
01/2023 - 12/2013
2Rare Diseases (Rare Disease)
01/2021 - 01/2020
2Virus Diseases (Viral Diseases)
01/2016 - 09/2005
2Erythropoietic Protoporphyria
09/2015 - 07/2012
2Starvation
06/2015 - 06/2006
2Neoplasm Metastasis (Metastasis)
02/2015 - 09/2003
2Hepatitis C
11/2013 - 10/2011
2Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
01/2012 - 08/2009
2Hyperplasia
01/2011 - 03/2004
2Chronic Pancreatitis
04/2008 - 05/2006
2Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
07/2007 - 05/2006
2Adenocarcinoma
06/2007 - 09/2006
2Barrett Esophagus (Barrett's Esophagus)
06/2007 - 09/2006
1Pachyonychia Congenita (Jadassohn-Lewandowsky Syndrome)
12/2023
1Hyponatremia
10/2023
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2022
1Systemic Mastocytosis
12/2022
1Cholestasis
01/2022
1Erythropoietic Porphyria (Congenital Erythropoietic Porphyria)
01/2021
1Inborn Genetic Diseases (Disease, Hereditary)
01/2021

Drug/Important Bio-Agent (IBA)

46Keratins (Keratin)IBA
12/2023 - 02/2002
24K-18 conjugate (K18)IBA
01/2023 - 05/2003
16Proteins (Proteins, Gene)FDA Link
10/2023 - 05/2003
10Keratin-8 (Keratin 8)IBA
12/2015 - 05/2003
6EnzymesIBA
11/2023 - 11/2005
6LaminsIBA
01/2023 - 07/2013
6Phosphotransferases (Kinase)IBA
12/2022 - 03/2002
6PorphyrinsIBA
01/2021 - 09/2015
5Acetaminophen (Paracetamol)FDA LinkGeneric
11/2023 - 09/2010
5Heme (Haem)IBA
01/2021 - 01/2016
4Lamin Type A (Lamin A)IBA
01/2023 - 06/2017
4AntibodiesIBA
10/2019 - 08/2003
4CeruletideIBA
01/2018 - 10/2004
4Keratin-18 (Keratin 18)IBA
12/2015 - 08/2003
4DNA (Deoxyribonucleic Acid)IBA
09/2006 - 05/2003
3Biomarkers (Surrogate Marker)IBA
11/2023 - 01/2016
3protoporphyrin IXIBA
01/2019 - 09/2015
3NF-kappa B (NF-kB)IBA
01/2018 - 10/2004
3Transcription Factors (Transcription Factor)IBA
01/2018 - 10/2012
3LipidsIBA
01/2016 - 09/2003
3CaspasesIBA
01/2016 - 04/2011
3Intermediate Filament ProteinsIBA
12/2015 - 03/2005
3Messenger RNA (mRNA)IBA
11/2013 - 10/2004
3Hemin (Panhematin)FDA Link
05/2011 - 11/2005
2ImmunosorbentsIBA
11/2023 - 01/2016
2Nuclear Proteins (Protein, Nuclear)IBA
01/2023 - 07/2013
2Adenosine (Adenocard)FDA LinkGeneric
10/2019 - 11/2013
25'-Nucleotidase (5' Nucleotidase)IBA
10/2019 - 12/2014
2CateninsIBA
01/2019 - 06/2013
2Deferoxamine (Desferal)FDA LinkGeneric
01/2019 - 09/2015
2Oxygen (Dioxygen)IBA
01/2018 - 10/2012
2Ethanol (Ethyl Alcohol)IBA
01/2018 - 10/2012
2BuffersIBA
11/2017 - 07/2013
2Choline (Choline Chloride)IBA
01/2017 - 11/2005
2EpitopesIBA
01/2016 - 02/2006
2AcidsIBA
09/2015 - 06/2007
2UbiquitinIBA
11/2013 - 09/2008
2sphingosine phosphorylcholineIBA
05/2012 - 09/2003
2Amino AcidsFDA Link
01/2012 - 05/2006
2Alanine Transaminase (SGPT)IBA
10/2011 - 04/2011
2Anti-Bacterial Agents (Antibiotics)IBA
01/2011 - 05/2005
2Heme Oxygenase-1IBA
01/2011 - 11/2005
1Ligases (Synthetase)IBA
11/2023
1Carbamyl Phosphate (Carbamoyl Phosphate)IBA
11/2023
1Urea (Carbamide)FDA LinkGeneric
10/2023
1Carrier Proteins (Binding Protein)IBA
01/2023
1parthenolideIBA
01/2023
1midostaurinIBA
12/2022
1isothiocyanic acidIBA
01/2022
1Uroporphyrinogen III Synthetase (Uroporphyrinogen-III Synthase)IBA
01/2021
1AcitretinFDA Link
01/2021
1coproporphyrin IIBA
01/2021
1Polysaccharides (Glycans)IBA
10/2019

Therapy/Procedure

5Therapeutics
12/2023 - 05/2005
1Ligation
01/2022
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
01/2021
1Immunotherapy
10/2019